COSMOSIL
5C18-MS-II
The
COSMOSIL 5C18-MS-II column, taking advantage of a new end
capping treatment can replace the COSMOSIL 5C18-MS. The silica
gel is end capped with polar groups for shielding effect,
based on the chemical property of the packed silica gel to
draw highly polar components from the mobile phase. As a result,
the new end capping provides improved peak shape for basic
compounds. The absorption of the silica gel is controlled
because it does not interact with N atoms, therefore suitable
for the separation of chelating compounds. Another advantage
is that the 5C18-MS-II has similar retention characteristics
to the 5C18-MS series: the HPLC conditions for the 5C18-MS
are applicable to the newly developed column, 5C18-MS-II.
MATERIAL
CHARACTERISTICS |
| |
COSMOSIL
5C18-MS-II |
Silica
gel |
high
purity porous spherical silica |
Average
particle size |
5
µm |
Average
Pore size |
approx.
120Å |
Specific
surface area |
approx.
300m2/g |
Stationary
phase |
monomeric
type octadecyl group |
Carbon
content |
approx.
16% |
Stability
under alkaline condition |
The
durability under extremely high pH is greatly improved
at the new COSMOSIL 5C18-MS-II compared with
current COSMOSIL 5C18-MS. Though it is possible
to use under alkaline condition for a limited time,
after long exposure some deterioration may occur. For
long use we recommend pH 7.5 and below.
Stability
under alkaline condition
Method: After the indicated length of incubation with the extremely
high pH buffer, the column was washed and the effective
plate number (N) for n-amylbenzene was measured.
The figure above shows the change in N as a function
of incubation time. There is hardly any observed change
in MS-II. On the other hand with MS when 10 hours or
more passed rapid deterioration was observed.
Alkaline solution;0.02M phosphate buffer (pH10.0) |
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| Catalog
# |
Cosmosil 5C18-MS-II Column |
Price ($U.S.) |
- |
| 02824-31 |
5C18-MS-II - Semi-mirco bore Column, 1.0 x 50mm |
$290.00 |
 |
| 02896-01 |
5C18-MS-II - Semi-micro bore Column, 1.0 x 150mm |
$390.00 |
|
| 093-8025 |
5C18-MS-II - Analytical Column, 2.0 x 150mm |
$390.00 |
|
| 34245-31 |
5C18-MS-II - Analytical Column, 3.0 x 150mm |
$390.00 |
|
| 34254-11 |
5C18-MS-II - Analytical Column, 3.0 x 250mm |
$450.00 |
|
| 093-8017 |
5C18-MS-II - Analytical Column, 4.6 x 50mm |
$230.00 |
|
| 093-8018 |
5C18-MS-II - Analytical Column, 4.6 x 100mm |
$330.00 |
|
| 093-8019 |
5C18-MS-II - Analytical Column, 4.6 x 150mm |
$350.00 |
|
| 093-8020 |
5C18-MS-II - Analytical Column, 4.6 x 250mm |
$390.00 |
|
| 093-8021 |
5C18-MS-II - Analytical Column, 6.0 x 150 mm |
$360.00 |
|
| 093-8022 |
5C18-MS-II - Analytical Column, 6.0 x 250 mm |
$560.00 |
|
| 093-8023 |
5C18-MS-II - Semi-preparative, 10.0 x 250mm mm |
$900.00 |
|
| 093-8024 |
5C18-MS-II - Preparative, 20.0 x 250mm |
$1,800.00 |
|
| 093-8014 |
5C18-MS-II - Analytical Guard Column, 4.6 x 10.0 mm |
$190.00 |
|
| 093-8016 |
5C18-MS-II - Semi-preparative Guard Column, 10.0 x 20 mm |
$325.00 |
|
| 380-1590 |
5C18-MS-II - Guard Cartridge Kit, Contains 3 guard and holder |
$400.00 |
|
| 380-1589 |
5C18-MS-II - Guard Cartridge, Contains 3 guard |
$200.00 |
|
|
